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Gonorrhoea

Rising Cases & Antibiotic Resistance: Know the Facts

Gonorrhoea cases have doubled in a decade. Antibiotic-resistant strains are emerging. Multi-site testing is essential. Get tested with results in 2 days.

What is Gonorrhoea?

Gonorrhoea is a bacterial STI caused by Neisseria gonorrhoeae that can infect the genitals, rectum, and throat. Cases have risen dramatically in recent years, and the emergence of antibiotic-resistant strains is a major public health concern. Untreated gonorrhoea can cause serious complications including infertility, and increases HIV transmission risk.

Symptoms

  • Men: Thick yellow or green urethral discharge
  • Men: Pain or burning when urinating
  • Men: Testicular pain or swelling
  • Women: Increased or changed vaginal discharge
  • Women: Pain when urinating
  • Women: Bleeding between periods or after sex
  • Rectal: Pain, discharge, itching, bleeding
  • Throat: Usually no symptoms, or mild sore throat
  • Many infections (especially in women) are asymptomatic

Causes

  • Infection with Neisseria gonorrhoeae bacteria
  • Transmitted through vaginal, anal, or oral sex
  • Can infect multiple sites simultaneously
  • Mother-to-baby transmission during birth
  • Sharing sex toys without proper cleaning
  • NOT spread through casual contact or toilet seats

Who Is at Risk?

  • Men who have sex with men (highest rates)
  • Young adults (15-24 years)
  • People with multiple partners
  • Those not using condoms
  • People with a history of STIs
  • Those whose partners have gonorrhoea

Potential Complications

  • Pelvic inflammatory disease (PID) in women
  • Infertility in both sexes
  • Ectopic pregnancy
  • Epididymitis in men
  • Disseminated gonococcal infection (rare but serious)
  • Increased HIV transmission
  • Neonatal eye infection (ophthalmia neonatorum)

How We Diagnose

Gonorrhoea is diagnosed using NAAT/PCR testing, which is highly sensitive and specific. We test from all relevant sites based on sexual history - urine and/or urethral swab, vaginal/cervical swab, throat swab, and rectal swab. Testing multiple sites is crucial as infections at different sites are often independent.

Treatment Options

Due to antibiotic resistance, UK guidelines now recommend dual therapy: ceftriaxone injection plus azithromycin. A test of cure is recommended 2 weeks after treatment to confirm clearance. All recent partners need testing and treatment. Avoid sex until you and your partner(s) have completed treatment and test of cure is negative.

Prevention

Consistent and correct condom use
Regular STI screening if at risk
Reducing number of partners
Testing before new sexual relationships
Avoiding sex while being treated
Partner notification and treatment

Frequently Asked Questions

Why is gonorrhoea becoming resistant to antibiotics?

Gonorrhoea has developed resistance to almost every antibiotic used against it over the decades. This is why we now use dual therapy. Treatment-resistant cases are monitored nationally. Always complete your treatment and attend test of cure.

Can I have gonorrhoea in my throat without symptoms?

Yes, throat gonorrhoea is usually asymptomatic or causes only mild symptoms. It's commonly missed if not specifically tested. If you've had oral sex, request a throat swab as part of your STI screen.

How soon after exposure can I test?

PCR testing can detect gonorrhoea from about 2 days after exposure, though we often recommend testing at 2 weeks for optimal accuracy. If you have symptoms, test immediately regardless of timing.

My partner tested negative but I'm positive - how?

Possible explanations include: your partner was tested too early, they weren't tested from all relevant sites, they had a different source of infection, or (rarely) a false negative result. Both partners should be retested if there's discrepancy.

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