15, Oct, 2025

HPV for Adults: Do You Still Need the Vaccine and Screening if You Are Over 25?

Many people think the human papillomavirus, or HPV, is a concern only for teenagers and young adults. In the UK, school programmes offer the HPV vaccine at age 12 to 13, so it is easy to assume the moment has passed once you are older. The reality is different. HPV remains common throughout adult life, vaccination can still help many people over 25, and screening remains important for early detection of changes that could lead to cancer. Here is what you need to know, plus practical steps you can take now.

A quick refresher on HPV

HPV is a group of more than one hundred viruses. Some types cause genital warts, others are high risk types that can lead to cell changes and, over time, cancers of the cervix, anus, penis, vulva and the back of the throat. Most sexually active people encounter HPV at some point. In many cases the immune system clears the infection without treatment. Persistent infection with high risk types is the concern, which is why vaccination and screening make a powerful combination.

Can adults over 25 benefit from the HPV vaccine

Yes, many can. The vaccine works by training your immune system to recognise and defend against the types most often linked to cancer and genital warts. It cannot treat an infection you already have, but it can still offer protection against types you have not yet encountered. Since people can acquire new HPV types with new partners at any age, vaccination can be useful beyond the teenage years.

Who might consider vaccination after 25

People with new or multiple partners
Those who did not receive the vaccine at school
People in new long term relationships who want added reassurance
Men who have sex with men, who may not benefit from cervical screening but can benefit from vaccine protection

If you are unsure whether vaccination would help you, a short consultation can clarify your personal risk and your likely benefit.

👉 Want tailored advice on HPV vaccination? Book a confidential consultation at STI Clinic.

What about screening if you are over 25

Screening and vaccination work together. Vaccination reduces risk, screening looks for early cell changes so they can be managed before cancer develops.

For people with a cervix

In England, routine cervical screening invitations usually begin at age 25.
Screening now tests primarily for high risk HPV, then checks cells if HPV is found.
Even if you are vaccinated, you should still attend screening when invited. The vaccine does not cover every HPV type, and screening catches issues early when treatment is simple.

For others without a cervix

There is no national screening programme for penile or anal cancers, but some people at higher risk may be advised to have targeted checks.
If you notice persistent symptoms, such as anal or genital bleeding, new lumps, long lasting soreness or changes in the mouth or throat, seek assessment promptly.

👉 If you are overdue a sexual health check, arrange a discreet screen at STI Clinic

Common myths that hold adults back

I am in a long term relationship, so I do not need the vaccine.
Many couples remain monogamous, which lowers risk. Life can change, new relationships can occur, and HPV exposure can happen later. Vaccination is a long term investment in protection.

I had HPV in the past, so there is no point vaccinating.
Past infection with one type does not protect against others. The vaccine covers key high risk types and types linked to warts, so there can still be meaningful benefit.

I am vaccinated, so I can skip screening.
Screening remains essential. The vaccine does not cover every type and does not treat an infection that is already present.

Only women need to worry about HPV.
HPV affects all genders. It is linked to anal, penile and oropharyngeal cancers as well as cervical cancer. Men can benefit from vaccination and from seeking assessment if symptoms arise.

Practical steps for adults over 25

Consider HPV vaccination if you missed it at school or if your circumstances have changed.
Keep up with cervical screening if you have a cervix. Attend when invited, even if vaccinated.
Use condoms and dental dams to lower the chance of HPV and other STIs, especially with new partners.
Avoid smoking, which is linked to a higher risk of persistent HPV infection and cervical cell changes.
Book a sexual health screen if you have had new partners or if you notice symptoms such as persistent genital warts, unexplained bleeding or long lasting mouth or throat changes.

👉 Unsure where to start? Speak to a clinician and plan your next steps at STI Clinic.

What to expect from vaccination and screening

HPV vaccination is given in a simple injection schedule, typically two or three doses depending on age and clinical guidance. Side effects are usually mild, such as a sore arm. Cervical screening involves a quick sample from the cervix that is tested for high risk HPV. If HPV is detected, a closer look at the cells may be arranged. Early changes can be monitored or treated before they cause problems.

Take Control of HPV Risks

Schedule your HPV test and discuss vaccination options with our experts. Early prevention matters, no matter your age.

The practical takeaway

HPV does not belong only to teenage years. Adults over 25 can still benefit from vaccination, especially if relationships change or if they missed the vaccine at school. Screening remains vital because it catches early changes that can be treated well before cancer develops. Add sensible protection, routine sexual health checks and prompt assessment of any persistent symptoms, and you have a strong, practical plan.

👉 Ready to make an informed move? Book HPV vaccination advice or a sexual health screen with STI Clinic today.