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What is Epididymitis?
Epididymitis is inflammation of the epididymis, the coiled tube at the back of the testicle that stores and carries sperm. In sexually active men under 35, it's most commonly caused by STIs, particularly chlamydia and gonorrhoea. In older men, it's more often related to urinary tract infections or prostate problems. Prompt treatment is essential to prevent complications.
Symptoms
- Gradual onset of testicular pain
- Swelling of one or both testicles
- Scrotum feels warm to touch
- Redness of scrotal skin
- Pain that worsens over hours to days
- Fever and chills
- Urethral discharge
- Pain when urinating
- Pain during ejaculation
Causes
- Chlamydia trachomatis (most common in young men)
- Neisseria gonorrhoeae
- E. coli and other urinary bacteria (more common over 35)
- Mycoplasma genitalium
- Urinary tract infections
- Prostate infections
- Recent urinary catheterisation or surgery
- Tuberculosis (rare)
Who Is at Risk?
- Sexually active men under 35
- Men with multiple sexual partners
- Men who have unprotected sex
- Men who have sex with men
- Men with recent urinary tract procedures
- Men with prostate enlargement or abnormalities
Potential Complications
- Abscess formation
- Chronic epididymitis
- Reduced fertility
- Spread of infection to the testicle (epididymo-orchitis)
- Scrotal fistula (rare)
- Testicular atrophy (rare)
How We Diagnose
Diagnosis involves physical examination showing tender, swollen epididymis, often with fever. We perform urine tests and urethral swabs for STI screening (chlamydia, gonorrhoea, mycoplasma). Ultrasound may be used to rule out testicular torsion - a surgical emergency that presents similarly. Blood tests may check for signs of infection.
Treatment Options
Treatment involves antibiotics targeting the likely cause. For sexually transmitted epididymitis, guidelines recommend ceftriaxone injection plus doxycycline. For UTI-related cases, fluoroquinolones or other antibiotics are used. Supportive care includes rest, scrotal elevation, ice packs, and anti-inflammatory painkillers. Sexual partners need testing. If your results indicate epididymitis, please take them to your GP or specialist for treatment.
Prevention
Frequently Asked Questions
Is epididymitis serious?
It can be if untreated. While most cases resolve with antibiotics, complications include abscess formation, chronic pain, and fertility problems. Importantly, sudden testicular pain needs urgent assessment to rule out testicular torsion, which is a surgical emergency.
How long does epididymitis take to heal?
With appropriate antibiotics, pain usually improves within a few days, but complete resolution of swelling can take several weeks. It's important to complete the full antibiotic course even if you feel better. Avoid heavy lifting and sexual activity until fully recovered.
Can epididymitis affect fertility?
If treated promptly, fertility is usually preserved. However, severe or recurrent infections can cause scarring that blocks sperm transport. Bilateral (both sides) involvement carries higher fertility risks. Early treatment is key.
Should I go to A&E for testicular pain?
Sudden, severe testicular pain needs urgent assessment to rule out testicular torsion, which requires emergency surgery. If pain developed gradually over hours/days with other symptoms, same-day GP or sexual health clinic assessment is appropriate.
Related Articles
Chlamydia vs. NSU (Non-Specific Urethritis): Which Test Do You Need?
Urethral burning or discharge does not always mean an STI, but symptoms can overlap with chlamydia and non-specific urethritis. Learn how the conditions differ and when testing may help.
Why Chlamydia Symptoms in Men Often Mimic a UTI
Chlamydia and urinary tract symptoms can look strikingly similar in men, making self-diagnosis unreliable. Learn how the symptoms overlap, when testing may help, and when urgent medical review is sensible.
Burning After Ejaculation: Why Men Should Screen for Chlamydia
Experiencing a burning sensation after ejaculation can be uncomfortable and alarming. Whilst this symptom can have several possible causes — many unrelated to STIs — chlamydia screening may be a sensible step for anyone with potential exposure or persistent discomfort.
Concerned About Epididymitis?
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